If you have a hard time swallowing them whole, ask your provider about the oral suspension. BK virus can affect how your kidney works and cause your transplanted kidney to fail, hepatitis B and C viruses. Other interactions can increase side effects or make them more severe. A boxed warning is the most serious warning from the FDA. However, hair loss is a possible side effect of other drugs that are used with CellCept to help prevent organ rejection, such as tacrolimus (Prograf). In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug). CellCept oral suspension contains aspartame (a source of phenylalanine). You also shouldnt donate semen while taking this drug. Using more than the recommended dosage of CellCept can lead to serious side effects. It isnt known how many people may have had unexplained weight loss after using CellCept in clinical studies. Other drugs are available that can prevent organ rejection. It can also interact with certain supplements as well as certain foods. CellCept is metabolized (broken down) in the body by a process called glucuronidation. This happens because the immune system doesnt recognize the new organ as part of your body. Isavuconazole, an antifungal medication, is an example of a drug that can affect how CellCept is broken down in the body. If you would like to notify the FDA about a side effect youve had with CellCept, you can do so through MedWatch. Before you start using CellCept, be sure to tell your doctor if you take any PPIs. While outdoors, wear a broad-spectrum sunscreen with a high protection factor. (Having a stable transplant means you arent experiencing any symptoms of organ rejection. Note: Some of the drugs listed here are used off-label to treat these specific conditions. However, if you do have any of these symptoms, tell your doctor right away so they can treat your condition. This can include setting an alarm on your phone or downloading a reminder app. CellCept is available as a generic drug called mycophenolate mofetil. The actual price youll pay depends on your insurance plan, your treatment plan, your location, and if applicable, the pharmacy you use. Examples of antibiotics that may need to be avoided while taking CellCept include: Be sure to tell your doctor if youre taking any antibiotics while using CellCept. In most cases, you should avoid getting live vaccines while taking CellCept. Food affects how the body absorbs mycophenolate. It is usually taken twice a day on an empty stomach (1 hour before or 2 hours after eating or drinking), unless your doctor tells you otherwise. The results showed that: The percentage of adults who had anemia after taking these drugs varied depending on the condition being treated. If you have unused medication that has gone past the expiration date, talk with your pharmacist about whether you might still be able to use it. These include: The following information describes dosages that are commonly used or recommended. Researchers are also looking into other uses. Its approved for use in adults and children ages 3 months and older. However, clinical studies have shown CellCept to be an effective treatment for this condition in adults and in children. As with all medications, the cost of CellCept can vary. They may have a preference for one version or the other. are pregnant or plan to become pregnant. Females who take Cellcept during pregnancy have a higher risk of miscarriage during the first 3 months (first trimester), and a higher risk that their baby will be born with birth defects. Generics tend to cost less than brand-name drugs. Your childs doctor will know how to calculate your childs body surface area to determine the correct dose. These serious infections can include: Call your doctor right away if you have any of the following signs and symptoms of infection: SeeWhat are the possible side effects of CellCept?for information about other serious side effects. CellCept is primarily metabolized by glucuronidation and is excreted into the urine. * CellCept and Myfortic have boxed warnings for these side effects. The expiration date helps guarantee that the medication is effective during this time. This could raise your blood levels of CellCept and increase your risk for side effects from CellCept. This lowers your immune systems ability to attack a newly transplanted organ. (Azathioprine is an antirejection drug like CellCept. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. You should avoid getting live vaccines while taking CellCept. Both drugs were given with corticosteroids and cyclosporine (Neoral, Sandimmune). Available for Android and iOS devices. (For more information, see the Taking CellCept with food section below.). Both drugs belong to a group of medications called immunosuppressants (drugs that weaken your immune system). Serious infections can happen with CellCept and can lead to hospitalizations and death. Phosphate binders are a group of drugs that are used to remove high levels of phosphate from your body. To help make sure you dont miss a dose, try using a medication reminder. If youre receiving the CellCept IV infusion, the dose is given by your doctor over a period of about 2 hours, twice per day. Cellcept can cause serious side effects, including: Increased risk of loss of a pregnancy (miscarriage) and higher risk of birth defects. This helps ensure you have a consistent amount of the drug in your body. CellCept is a type ofimmunosuppressant drug (also known as an antirejection drug). Both drugs were given with corticosteroids and cyclosporine (Neoral). The capsule forms of both drugs are typically taken twice per day. For more information, see Boxed warnings under Side effect details below. A kitchen timer can work, too. plan to receive any vaccines. This means taking your dose either 1 hour before eating or 2 hours after eating. CellCept is FDA-approved to help prevent organ rejection after a heart, kidney, or liver transplant in combination with other immunosuppressants. Very Important A change in your diet, medicine, or dosage may be necessary. Here are answers to some frequently asked questions about CellCept. The CellCept infusion is given over a period of about 2 hours, twice per day. If you are a female . Both CellCept and Myfortic are FDA-approved to help prevent organ rejection after a kidney transplant in adults and in children. If you have not told your doctor about any of the above, do so before you start taking CellCept. (For more information, see the CellCept side effects section above.). It isnt known how many people who used a placebo may have had depression. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Treatment failure was defined as: The percentage of adults who experienced treatment failure varied depending on the dose being studied and the country where the study took place. prednisone, triamcinolone, prednisolone, tacrolimus, azathioprine, cyclosporine, mycophenolate mofetil, cyclophosphamide, cortisone, Imuran. If you throw up after: less than 30 minutes: repeat the full mycophenolate dose (repeat the dose only once) more than 30 minutes: do not repeat the dose Many of these side effects may go away within a few days or a couple of weeks. prednisone, triamcinolone, prednisolone, tacrolimus, azathioprine, cyclosporine, mycophenolate mofetil, cyclophosphamide, cortisone, Imuran. We comply with the HONcode standard for trustworthy health information. Prograf is available as a generic drug called tacrolimus. In this situation, your doctor may give you the CellCept infusion for up to 14 days. Your use of third-party websites is at your own risk and subject to the terms and conditions of use for such sites. CellCept is used to prevent organ rejection in patients who are at least three months of age who have received a liver transplant, a heart transplant, or a kidney transplant. People who take CellCept have a higher risk of getting lymphoma, and other cancers, especially skin cancer. Prednisone can also cause a redistribution of fat to the face, back of the neck and the abdomen, although these changes vary from person to person. (Cancer is a possible serious side effect of CellCept. This may occur if you develop an infection or have an existing infection that worsens. Also, tell your doctor if you have unusual tiredness, lack of energy, dizziness or fainting. They can be prescribed to adults and children.. These lists contain up to 10 of the most common mild side effects that can occur with each drug, or with both CellCept and Prograf (when taken individually). These lists dont include all possible side effects that may occur with each drug. Keep a list of them to show to your doctor or nurse and pharmacist when you get a new medicine. Avoid combinations; the risk of the interaction outweighs the benefit. Some vaccines may not work as well during treatment with CellCept. Choose high-fiber whole grains like: Whole wheat bread or grains made with whole wheat flour. Specifically, CellCept is a type of immunosuppressant called an antirejection drug. They make your body less likely to reject a transplanted organ. Myfortic was found to be as effective as CellCept at preventing organ rejection. Do not stop taking CellCept or change the dose unless your doctor tells you to. Organ rejection occurs when the immune system attacks a transplanted organ. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Read More. In this situation, your doctor may give you the CellCept infusion for up to 14 days. If you miss a dose of CellCept, or you are not sure when you took your last dose, take your prescribed dose of CellCept as soon as you remember. CellCept is rapidly absorbed and converted to its active metabolite, mycophenolic acid. Taking CellCept with drugs that are cleared from the body in this way can increase the levels of these drugs in your body. These lists dont include all possible side effects. If you think youve taken too much of this drug, call your doctor. They can help determine if these medications will affect the breakdown of CellCept in your body. CellCept contains the active ingredient mycophenolate mofetil. (Organ rejection occurs when the immune system attacks a transplanted organ.). * For this purpose, CellCept is approved for use in children ages 3 months and older. If you get pregnant while taking CellCept, do not. People taking CellCept should avoid eating at least 1 hour before and 2 hours after taking a dose. This means taking your dose either 1 hour before eating or 2 hours after eating. Its also supported by additional data from use in children. This is because live vaccines generally require a healthy immune system to be effective. Storage requirements for CellCept vary with each formulation: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Anemia (low number of red blood cells) may happen while taking CellCept. To learn about the cost of CellCept infusion, talk with your doctor. If your doctor has prescribed CellCept and youre interested in using mycophenolate mofetil instead, talk with your doctor. However, chemotherapy drugs cant tell the difference between healthy cells and cancer cells. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. Specifically, CellCept is a type of immunosuppressant called an antirejection drug. Capsules should be stored at room temperature. (Mycophenolate is the active drug in CellCept). This lowers your immune systems ability to attack the newly transplanted organ. Don't open, cut, crush, or chew them. The purpose of this registry is to gather information about the health of you and your baby. However, clinical guidelines recommend using CellCept for lupus in adults who also have signs of kidney disease. No, CellCept isnt a chemotherapy drug. Enter other medications to view a detailed report. If youre receiving the CellCept IV infusion, the typical dosage is 1,000 mg given twice per day. Is the ketogenic diet right for autoimmune conditions? Warnings CellCept has been found effective for preventing organ rejection after a heart, kidney, or liver transplant in adults and children ages 3 months and older in combination with other immunosuppressants. However, live vaccines could cause infections in people whose immune systems are weakened, including those taking immunosuppressants such as CellCept. This happens because the immune system doesnt recognize the new organ as part of your body. Chemotherapy drugs work by destroying all cells that are growing quickly. Prograf contains the active ingredient tacrolimus. You may need to avoid crowds and wash your hands often. Do not crush, chew, or split the tablets. We comply with the HONcode standard for trustworthy health information. Before approving coverage for CellCept, your insurance company may require you to get prior authorization. This card may help lower the cost of the drug for you. CellCept is available in other forms, including a liquid that you swallow and an infusion thats given by a healthcare professional. CellCept can affect your ability to drive or operate machines. Generics tend to cost less than brand-name drugs. Tell them about all prescription, over-the-counter, and other drugs you take. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. * CellCept and Prograf have boxed warnings for these side effects. Minimally clinically significant. Your doctor will likely check your red blood cell count before you start using CellCept. This means taking your dose either 1 hour before eating or 2 hours after eating. This reaction is a natural process that happens in your body when your immune system detects other unknown substances, such as bacteria. This is because drinking alcohol can lead to health problems that cause extra strain on your transplanted organ, such as hypertension (high blood pressure). How long a medication remains good can depend on many factors, including how and where you store the medication. Taking CellCept with certain birth control pills can make these pills less effective. Its also available as an intravenous (IV) infusion* (an injection into a vein over a period of time) thats given by your doctor. A boxed warning is the most serious warning from the FDA. Symptoms of organ rejection may include: Its important to note that having symptoms of organ rejection doesnt necessarily mean that your transplant has failed or that youll need another transplant. Examples of birth control pills that contain levonorgestrel include Seasonique and Twirla. Possibly. Usually avoid combinations; use it only under special circumstances. increased risk of developing a food-related infection. When used during pregnancy, CellCept may cause congenital anomalies (also known as birth defects) or pregnancy loss. Weight gain wasnt a side effect reported in clinical studies of CellCept. After 12 months of treatment: These results were similar to the results observed in adults using CellCept for kidney transplants. Severe Interactions These medications are not usually taken together. Treating scleroderma isnt an FDA-approved use for CellCept. Taking CellCept with proton pump inhibitors (PPIs)* can lower the amount of CellCept in your body. For instance, some interactions can interfere with how well a drug works. CellCept weakens the bodys immune system and affects your ability to fight infections. Examples of immunosuppressants used with CellCept include corticosteroids and cyclosporine (Neoral, Sandimmune). For more information, see the Boxed warnings section above.) Genentech does not recommend and does not endorse the content on any third-party websites. If you have questions about whether CellCept is right for your child, talk with their doctor. There is 1 alcohol/food interaction with CellCept (mycophenolate mofetil). Myfortic is available as a generic drug called mycophenolate sodium. Call your doctor if you are not sure what to do. CMV can cause serious tissue and blood infections, BK virus. To learn about other mild side effects, talk with your doctor or pharmacist, or view CellCepts Medication Guide. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. For information on how the drug performed in clinical studies, see CellCepts prescribing information. Receiving this medicine while you are pregnant can harm your unborn baby. Highly clinically significant. Granulocyte colony stimulating factor (G-CSF) is a type of drug that doctors prescribe to manage neutropenia. Try to take your doses around the same time each day. CellCept is used with other antirejection drugs to help prevent organ rejection* in adults and in children ages 3 months and older. If youre taking cholestyramine, be sure to tell your doctor before using CellCept. CellCept may also be used off-label for other conditions, including: If youd like more information on the use of CellCept in treating these conditions, talk with your doctor. Taking CellCept can increase your risk for serious infections. Weight gain is a common side effect of prednisone. Genentech, the manufacturer of CellCept, offers the CellCept Co-pay Card. Take mycophenolate (CellCept) every 12 hours on an empty stomach, unless your healthcare provider has told you to take it with food. CellCept is an immunosuppressant (a drug that weakens your immune system). Generics tend to cost less than brand-name drugs. To help prevent organ rejection, dont stop taking CellCept without first discussing the risks with your doctor. If you accidentally get the powder or oral suspension in your eyes or other mucous membranes, flush with plain water. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. For more information, see the CellCept dosage section below. If you are not able to swallow CellCept tablets or capsules, your doctor may prescribe CellCept Oral Suspension. (See. Theyll likely also check your red blood cell counts regularly during your treatment. If you arent having any symptoms of organ rejection, you may not notice CellCept working in your body. If youre not sure if youll need to get prior authorization for CellCept, contact your insurance company. You should have one pregnancy test right before starting CellCept and another one 8 to 10 days later. (Azathioprine is an antirejection drug, like CellCept.) If youre concerned about hair loss while using CellCept, talk with your doctor. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Examples of effective birth control include: Males who use CellCept should use effective birth control while taking the drug and for at least 90 days after their last dose. Do not mix CellCept Oral Suspension with any other medicine. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. It's recommended that you take the capsule or tablet with food and water, as this can stop you feeling sick and getting stomach pains. Your pharmacist will mix the medicine before you pick it up from a pharmacy. These lists contain examples of serious side effects that can occur with CellCept, with Prograf, or with both drugs (when taken individually). Its important to note that your results while using CellCept may vary from those seen in clinical studies. There are 6 disease interactions with CellCept (mycophenolate mofetil) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The recommended oral dosages in children are as follows: If you miss a dose of CellCept, take your missed dose as soon as you remember. CellCept is used with other immunosuppressant medicines containing cyclosporine and corticosteroids. Before taking CellCept, talk with your doctor about your health history. Precautions. Examples of birth control pills that contain levonorgestrel include Seasonique and Twirla. Moderately clinically significant. birth control pills (oral contraceptives). If taken with CellCept, these antacids can lower the amount of CellCept in your body. 2023 Genentech USA, Inc. All rights reserved. you are allergic to any other medicines, foods, dyes or preservatives. 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